Description of the fields in the Integrase Inhibitor Database (IIDB).

Field name (Label)

Type

Description

ID (ID)

Integer

Sequential serial number of the inhibitor

Structure (structure)

Structure

Chemical structure of the inhibitor

*fmla_structure (Formula)

Formula

Formula of the inhibitor

*mol.weight_structure (Molecular Weight)

Real

Molecular weight of the inhibitor

Name (Name)

Variable Text

Name of the inhibitor

Comments (Comments)

Variable Text

More collected information, or extra comments of the inhibitor

PURITY (PURITY)

Real

Purity information of the inhibitor

CAS (CAS)

Variable Text

CAS number of the inhibitor

NSC (NSC)

Variable Text

NSC number of the inhibitor

Reference (Reference)

Variable Text

Reference which reported this inhibitor; may have multiple values

Lab/Company (Lab/Company)

Variable Text

Lab or the company who reported this inhibitor; may have multiple values

Worker (Worker)

Fixed Text

Scientists in the corresponding reference who identified and/or assayed the inhibitor; may have multiple values

THREE_PRIME_ACTIVITY (3'-P)

Real

Inhibition activity against 3'-P, μM; the assay condition was not known from the reference; may have multiple values

STRAND_TRANSFER_ACTIVITY (ST)

Real

Inhibition activity against ST, μM; the assay condition was not known from the reference; may have multiple values

ThreeP_ACTIVITY_MG (3'-P (Mg))

Real

Inhibition activity against 3'-P, μM; the assay condition was not clear from the reference, but the metal cofactor was Mg2+; may have multiple values

ST_ACTIVITY_MG (ST (Mg))

Real

Inhibition activity against ST, μM; the assay condition was not clear from the reference, but the metal cofactor was Mg2+; may have multiple values

ThreeP_ACTIVITY_MN (3'-P (Mn))

Real

Inhibition activity against 3'-P, μM; the assay condition was not clear from the reference, but the metal cofactor was Mn2+; may have multiple values

ST_ACTIVITY_MN (ST (Mn))

Real

Inhibition activity against ST, μM; the assay condition was not clear from the reference, but the metal cofactor was Mn2+; may have multiple values

Antivirial_Activity (Antivirial_Activity)

Real

Antiviral potency of the inhibitor, EC50, μM; may have multiple values

Toxicity (TOXICITY)

Real

Cytotoxicity of the inhibitor, CC50, μM; may have multiple values

MG_WT_PIC_3P (WT_PIC_3P)

Real

Inhibition activity against 3'-P, μM; wild-type PIC was used and the metal cofactor was Mg2+; may have multiple values

MG_WT_PIC_ST (WT_PIC_ST)

Real

Inhibition activity against ST, μM; wild-type PIC was used and the metal cofactor was Mg2+; may have multiple values

MG_WT_PRINC_3P (WT_ PRINC _3P)

Real

Inhibition activity against 3'-P, μM; wild-type PRINC was used and the metal cofactor was Mg2+; may have multiple values

MG_WT_PRINC_ST (WT_ PRINC _ST)

Real

Inhibition activity against ST, μM; wild-type PRINC was used and the metal cofactor was Mg2+; may have multiple values

MG_MUT_PIC_3P (MUT_PIC_3P)

Real

Inhibition activity against 3'-P, μM; mutated PIC was used and the metal cofactor was Mg2+; may have multiple values

MG_MUT_PIC_ST (MUT_PIC_ST)

Real

Inhibition activity against ST, μM; mutated PIC was used and the metal cofactor was Mg2+; may have multiple values

MG_MUT_PRINC_3P (MUT_PRINC_3P)

Real

Inhibition activity against 3'-P, μM; mutated PRINC was used and the metal cofactor was Mg2+; may have multiple values

MG_MUT_PRINC_ST (MUT_PRINC_ST)

Real

Inhibition activity against ST, μM; wild-type PRINC was used and the metal cofactor was Mg2+; may have multiple values

MN_WT_PIC_3P (WT_PIC_3P)

Real

Inhibition activity against 3'-P, μM; wild-type PIC was used and the metal cofactor was Mn2+; may have multiple values

MN_WT_PIC_ST (WT_PIC_ST)

Real

Inhibition activity against ST, μM; wild-type PIC was used and the metal cofactor was Mn2+; may have multiple values

MN_WT_PRINC_3P (WT_ PRINC _3P)

Real

Inhibition activity against 3'-P, μM; wild-type PRINC was used and the metal cofactor was Mn2+; may have multiple values

MN_WT_PRINC_ST (WT_ PRINC _ST)

Real

Inhibition activity against ST, μM; wild-type PRINC was used and the metal cofactor was Mn2+; may have multiple values

MN_MUT_PIC_3P (MUT_PIC_3P)

Real

Inhibition activity against 3'-P, μM; mutated PIC was used and the metal cofactor was Mn2+; may have multiple values

MN_MUT_PIC_ST (MUT_PIC_ST)

Real

Inhibition activity against ST, μM; mutated PIC was used and the metal cofactor was Mn2+; may have multiple values

MN_MUT_PRINC_3P (MUT_PRINC_3P)

Real

Inhibition activity against 3'-P, μM; mutated PRINC was used and the metal cofactor was Mn2+; may have multiple values

MN_MUT_PRINC_ST (MUT_PRINC_ST)

Real

Inhibition activity against ST, μM; wild-type PRINC was used and the metal cofactor was Mn2+; may have multiple values

PIC: pre-integration complex. PRINC: principal complex.